A new study from the Department of Neuroscience at the Faculty of Health and Medical Sciences at the University of Copenhagen, published in Nature Neuroscience and titled “Spinal astroglial cannabinoid receptors control pathological tremor,” shows how cannabis could help those who suffer from pathological tremors.
According to the study, cannabinoids can interact with a certain type of star-shaped cell, called an astrocyte, in the spinal cord to help with tremors. Cannabinoids do this by regulating the release of purines and metabolites and regulating the transmission of electrical signals to the synapses.
The Study and Its Impact
In order to conduct the study, the research team used a mouse model to show how cannabis can help with tremors, conditions often brought on by trauma or neurodivergent disorders, that can cause uncontrollable shaking of the head or limbs. These conditions impact more than 200,000 people per year just in the U.S., so relief is much-needed.
“We have focused on the disease, essential tremor. It causes involuntary shaking, which can be extremely inhibitory and seriously reduce the patient’s quality of life. However, the cannabinoid might also have a beneficial effect on sclerosis and spinal cord injuries, for example, which also cause involuntary shaking,” said Jean-François Perrier, PhD,