Here’s my Pick of the Week’s News as published by Multiple Sclerosis News Today.
Now here’s a rare chance to get involved in a clinical trial – as long as you have MS and experience some form of spasticity.
A new clinical trial evaluating the effectiveness of extended-release baclofen capsules in relieving spasticity related to multiple sclerosis (MS) is calling for 135 people with any form of the disease. The study, taking place in six U.S. states, is sponsored by Sun Pharma, the drug’s developer.
Baclofen, an approved MS treatment available in different forms, acts as a muscle relaxer and an antispastic agent. As an extended-release treatment, Baclofen GRS distributes the drug’s active ingredients over time in a patient’s body, possibly allowing for less frequent dosing than is now common.
To take part, patients must be 18 or older and diagnosed with any form of MS, have a known history of spasticity, and already may be using baclofen in its current approved formulations.
Participants should have no clinical history of hypersensitivity to baclofen and no previous treatment with intrathecal baclofen, a method that delivers the drug directly to the intrathecal space (area of the spine) via a surgically implanted infusion pump and catheter.
Trial investigators will randomize participants to oral daily treatment with extended-release high-dose baclofen, low-dose baclofen, or placebo, for about 25 days. The trial, called Basis, lasts for 46 days, and three clinic visits will be required.
Doctor’s offices taking part in the study will be in these cities: Long Beach and San Diego, Calif.; Aurora, Colo.; Jacksonville, Miami, Miami Springs, Orlando, and Tampa, Fla.; Charlotte, N.C.; Cleveland, Ohio; and Richland, Wash.
More information about this trial, and how to participate, can be found on the trial’s website at www.basisstudy.com.